Welcome to the Tavassoli Research Group's website.

We are an interdisciplinary chemical biology research group, based in Chemistry at the University of Southampton. Our efforts are directed towards understanding cellular protein-protein interaction networks, and developing molecules that tackle diseases such as Cancer and HIV by targeting these protein networks.

If you are interested in joining us as a PhD student or a postdoctoral researcher, please contact us.



January 2015

Congratulations to Charlotte Lawrence for passing her PhD viva.


October 2014

We welcome Dr. Fiona Rown, Andrew Ball, Catrin Sohrabi, Joe Gibson and James Leverington to the lab.


September 2014

Several new papers published. Please see publications page.


July 2014

Ali talks about our CRUK-funded research to runners, joggers and walkers at the Southampton Race for Life.


July 2014

Congratulations to Abi for passing her PhD viva.


April 2014

Congratulations to Steph for passing her PhD viva.


March 2014

Two industrially funded PhD positions are available. Further information is available here and here. Please apply via the link at the bottom of each advert.


February 2014


January 2014

Our new publication in Angewandte Chemie, is highlighted by F1000Prime, Derek Lowe's In the Pipeline blog, and Chemistry World.


January 2014

Several new papers have been published by the lab. Please see the publication page.


January 2014

We welcome Dr. Mikie Kukwikila and Xiao Yang to the lab.


October 2013

We welcome PhD students Andrew Foster, James Ingram, Mira Kreuzer, Eilidh Leich, Katherine Lennard, and Eliot Osher to the group.


September 2013

New paper from our lab (in collaboration with Donna Davies' group) published in Molecular Biosystems.


September 2013

Ali opens the new CRUK shop in Guernsey.


August 2013

Elena's paper (in collaboration with Earl Brown's group in Ottawa) on the role of NS1 gene mutations on the virulence of influenza is published in Virology Journal.


August 2013

Cancer Research UK news story about our CtBP dimerization inhibitor.


August 2013

Some of the media coverage for our HIF-1 inhibitor paper:

ITV news, Free Press, Science Daily, Information Daily, Pharmaceutical Technology, The Daily Echo, The Business Standard, Pharma Times, Zee News, In the Pipeline, CRUK blog, and of course University of Southampton!

Charlotte Lawrence did a fantastic job explaining the paper on ITV television news, and Ali was interviewed by BBC radio.


July 2013

The first specific inhibitor of HIF-1 dimerization is published by the Tavassoli group in the Journal of the American Chemical Society.


July 2013

Tavassoli Chem Sci cover


June 2013

Funding news: We thank AstraZeneca, GlaxoSmithKline, Neusentis (Pfizer), Conformetrix, CRUK, EPSRC, BCC, Kerkut Trust, Wessex Trust and BBSRC for supporting our research.


older news items...